User blog comment:Brainwasher5/Smiter thoughts/@comment-2154860-20160122130431

Against the bosses of Uber Tristram, Open wounds is essential, and it's something that I don't see a lot of in your post. For eight seconds, you have cut the bosses off from their ability to regenerate which can outstrip some of the heaviest damage the characters can dish out. Gore Riders is good for 15%, but in my history with Uber Tristram runs with a Frenzy Barbarian, it was difficult to get it to trigger often enough at that level. And don't forget that you can stock charms with resistance bonuses as well.

I hope you're not thinking I'm trying to derail your train, just some stuff to consider given that I've tanked in four Uber Tristram runs and one of those was successful. I like to think that I've managed to learn from my mistakes.